The main three ways people will bet on an NFL game, however, are the Moneyline, Point Spread, and Points Totals. Each NFL match will have hundreds of different markets in which you can wager on, from betting on the winner of the game, to the point spread, or a whole host of Player Prop Bets such as touchdown scorers, the possibilities when betting an NFL game are near limitless. NFL is by some way the most popular sport to bet on across the US, and with the relative recency to sports betting, many people are left wondering how to bet on the NFL and the different ways in which you can.